Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

What You Will Achieve

Deliver results in a fast-paced matrix-oriented setting, be a contributor to key process purification steps and hold responsibility for various downstream process development activities. This advertised role is in support of products and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, therapeutic proteins, and polysaccharides in commercial operations and late-stage clinical development. The candidate will work across downstream purification functions, projects, and global sites.

In this role, you will:

• The MSAT downstream purification group is responsible for providing support to the upstream team, as well as downstream development purification/optimization, mRNA drug substance/drug product process activities, and providing support to routine manufacturing operations
• Candidate should have scientific knowledge and experience in techniques such as mRNA Drug Substance process, LNP formulation, UF/DF, Column Chromatograph, and ideally familiar with standard downstream equipment, e.g. AKTAs
• Familiar with concepts of process development and qualification of purification techniques.
• Ensure the proper and timely execution in all aspects of downstream processing to support group activities
• Perform scale-down purifications of biologics including enzymes using precipitation, depth filtration, ultrafiltration and chromatography under supervision of lab supervisor/designee
• Ensures effective, high-quality, timely and appropriate documentation in electronic laboratory notebooks and internal technical reports; presents data/ strategy to scientists and management in appropriate internal and external venues (technical meetings, project team meetings, conferences) as appropriate.
• Contributes to safe, efficient, effective and harmonious lab environment, ensures appropriate cleanliness and status/ operability of shared or assigned lab space or equipment; strong lab citizen and collaborative team player; approaches the job with energy and commitment; frequently demonstrates initiative.
• Participate in multi-disciplinary teams to resolve complex issues - Assist in manufacturing investigations and process troubleshooting - Assist on process improvement projects
• Participate in organizational initiatives aligning to Six Sigma practices

Here Is What You Need (Minimum Requirements)

• Applicant must have a Bachelor's degree with at least 2 years of experience; OR a Master's degree with 0+ years of experience; OR an Associate's degree with 6 years of experience; OR a high school diploma (or equivalent) and 8 years of relevant experience
• Experience with interdisciplinary drug development teams and industrial experience developing purification strategies and methods in support of product and process development and to assess the quality and characteristics of biotherapeutics.
• Demonstrated technical writing skills
• Experience with technologies focused on mRNA drug substance process such as In-vitro transcription reactions, LNP formulations, AKTA, UF/DF, Column Chromatography, mRNA drug substance/drug product operations

Bonus Points If You Have (Preferred Requirements)

• Demonstrated technical skills and scientific expertise in purification process development and troubleshooting
• Experience with Microsoft Office, Excel, Word, etc.
• Curiosity about seeking and applying current relevant scientific literature.

Physical/Mental Requirements

• Possess effective oral and written communication skills.

• Enthusiastic about communicating to a broad range of stakeholders (from novices to experts) and seeking agreement in complex situations.

• Change agile, functional in a fast-paced team environment where multi-tasking required.

Non-Standard Work Schedule, Travel, or Environment Requirements

• This role is standard day Monday through Friday work shift. May require some out of hours working to