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Principal Cloud & Infrastructure Engineer | Temporary FT & Onsite

Neurocrine Biosciences
San Diego, United Statesfull_timeVerifiedPosted 10 Mar 2026

About the role

Who We Are:

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs.

What We Do:

Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X and Facebook. (*in collaboration with AbbVie)

About the Role:

The Principal Cloud and Infrastructure Engineer serves as the senior technical authority responsible for designing, modernizing, and optimizing enterprise-scale Azure-centric cloud environments integrated with AWS and on-premises infrastructure. This role drives large-scale platform transformations including workload migration, infrastructure consolidation, automation-first provisioning, cost optimization, GxP-aware cloud environments, and performance engineering across hybrid architectures. The position requires deep expertise in Azure cloud engineering, strong AWS experience, and hands-on integration with VMware virtualization, enterprise storage, identity systems (AD/Azure AD), networking, and scientific compute platforms. The Principal Engineer defines platform strategy, establishes architectural standards, leads complex cross-functional programs, and ensures secure, compliant, highly available, and cost-efficient operations across the enterprise.

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Your Contributions (include, but are not limited to):

  • Lead large-scale technology infrastructure consolidation, virtualization, and cloud migration initiatives.

  • Drive automation-first engineering using Infrastructure as Code (Terraform, ARM/Bicep, CloudFormation) across cloud and on-prem environments.

  • Design and implement API-driven, self-service provisioning platforms integrated with ServiceNow and identity systems.

  • Lead cloud cost optimization and FinOps initiatives across Azure and AWS, including savings strategies and governance controls.

  • Architect and optimize VMware platforms with high availability, disaster recovery, and footprint reduction strategies.

  • Design scalable storage architectures across Azure, AWS (S3, FSx), and on-prem NetApp with automated tiering and lifecycle management.

  • Enable secure, on-demand compute platforms supporting containerized workloads (Docker/Kubernetes) and advanced analytics use cases.

  • Implement identity-driven access models using AD/Azure AD with policy-based provisioning and role-based controls.

  • Design and implement hybrid conne

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Company

Neurocrine Biosciences

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