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Senior Associate Scientist/Scientist, Discovery Toxicology

When you join BMS, you are joining a diverse, high-achieving team united by a common mission. 

The Pharmaceutical Candidate Optimization organization at Bristol Myers Squibb is a dynamic, multi-disciplinary department that works to discover and optimize new drug candidates.  We work across all therapeutic areas and all modalities (small molecules, biotherapeutics, gene and cell therapies and other novel modalities), and engage with all other R&D functions to advance new assets in the BMS portfolio.  Our integrated, cross-functional teams apply deep expertise in drug metabolism, pharmacokinetics (DMPK), toxicology, pharmaceutics, and bioanalysis to identify and solve issues, discover high quality drug candidates, and enable their clinical development.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Summary

We are seeking an innovative scientist to join the Discovery Toxicology laboratory at BMS San Diego. The Discovery Toxicology team supports the early-stage discovery of pharmaceuticals, including the identification, mechanistic investigation, and risk mitigation from initial target identification through to development candidate nomination. The scientist will serve as an integral member of the Discovery Toxicology team and conduct experiments to support the progression of assets within the discovery portfolio. The successful candidate will be expected to explore and evaluate novel assays and laboratory techniques to expand internal capabilities and contribute to the advancement of toxicology research. 

Key Responsibilities

• Design, execute, troubleshoot, and interpret in vitro cell culture and molecular biology experiments
• Develop and maintain clear assay protocols and data documentation to facilitate method sharing among scientists in Discovery Toxicology
• Learn to conduct analytical assays that can support broad-based mechanistic toxicology investigations
• Provide primarily in vitro and occasionally in vivo technical assistance to scientists within Discovery Toxicology
• Work collaboratively with functional experts across the organization to successfully execute projects

Basic Qualifications

• Bachelor’s degree in biology, pharmacology, immunology, toxicology, or biochemistry with 4 years of academic or industry experience
• Or
• Master’s degree with 2 years academic or industry experience

Preferred Qualifications

• Master’s degree in biology, pharmacology, immunology, toxicology, or biochemistry with 2 years academic or industry experience
• Exceptional organizational skills and laboratory/experimental documentation practices are critical
• Proficient mammalian cell culture skills and aseptic technique are required, experience in primary cell culture and/or 3D tissue culture is preferred but not required
• Experience in molecular biology techniques (e.g., ELISA, western blotting, multiplexed protein analysis, RT-PCR, gene editing, etc.) is required
• Exposure working with in vivo mammalian models is required including but not limited to rodent handling, test article administration, animal observation, sample collection, necropsy, data collection and documentation, etc.
• Ability to work in a collaborative, multidisciplinary team environment
• Good written and verbal communication skills are a must  

The starting compensation for this job is a range from $79,000 - $110,000 plus incentive cash