Scientific Director – Pathologist, Translational Pathology, Clinical Biomarkers and Diagnostics

Career Category

Job Description

HOW MIGHT YOU DEFY IMAGINATION?

If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

Scientific Director – Pathologist, Translational Pathology, Clinical Biomarkers and Diagnostics

Live

What you will do

Let’s do this. Let’s change the world. The use of Biomarkers and Diagnostics is central to understanding how our therapeutics work and identifying patients that benefit most from these therapies. Accordingly, the Clinical Biomarkers & Diagnostics (CBD) function, within Precision Medicine, plays a critical role in advancing our drug development programs and is accountable for the development of biomarker and diagnostics strategy across our pipeline. The CBD Translational Pathology group is responsible for implementing the biomarker and diagnostics strategy. We are seeking a highly motivated individual to provide pathology expertise and help drive implementation of tissue-based assays to support diagnostics and biomarker strategies. This individual will work closely with internal groups and external CROs/collaborators. This position will report directly to the Executive Director of Translational Pathology.

In this vital role you will successfully partner with cross-functional stakeholders to drive implementation of biomarker and diagnostics assay development

• The Translational Pathology Director will be accountable for the scientific strategy for and implementation of translational tissue-based biomarkers including patient selection, pharmacodynamic, and mechanism of resistance.
• The Translational Pathology Director will provide expertise in human disease pathology and experimental pathology for development and interpretation of tissue-based assays.
• The Translational Pathology Director will be accountable for delivering internal and external patient selection IHC and Molecular Dx assays and cutoffs across therapeutic areas through management of individual contributors, cross-functional relationships and external partnerships.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

DVM OR MD or Doctorate degree PhD OR PharmD [and relevant post-doc where applicable] and 5 years of translational or experimental pathology experience

Or

Master’s degree and 8 years of translational or experimental pathology experience

Or

Bachelor’s degree and 10 years of translational or experimental pathology experience

Preferred Qualifications:

• Highly experienced pathologist (MD or DVM degree) with 5+ years of relevant postdoctoral academic, clinical and/or industry pathology experience. PhD in addition to professional degree is a plus but not a requirement. Board certification in the United States is desirable but not required.
• A proven translational pathology track record with credible publications and strong molecular and/or experimental pathology supporting research and development
• Demonstrated expertise in tissue-based analysis such as in situ hybridization, immunohistochemistry, fluorescence applications, laser capture microdissection
• Expertise with human diseases and experimental mouse models
• Expertise with image analysis software and algorithm design
• In depth experience with the discovery, characterization, clinical validation, and utilization of tissue-based diagnostics
• Awareness of the challenges of implementing tissue-based biomarker and diagnostic technologies in the clinical setting
• Direct experience in development, outsourcing and validation of clinically applicable tissue based diagnostic assays
• Demonstrated excellence in independently leading and conducting research and ability to summarize information/data in a concise, easy to understand manner
• Excellent leadership skills including mentoring, motivation and delegation
• Excellent verbal and written communication and presentation skills
• High level of initiative and ability to work independently
• High level of business awareness

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

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